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What is Uterine Cancer or Endometrial Cancer?

Uterine cancer is the most common cancer occurring in a woman’s reproductive system. Uterine cancer begins when healthy cells in the uterus change and grow out of control, forming a mass called a tumour. A tumour can be cancerous or benign. A cancerous tumour is malignant, meaning it can grow and spread to other parts of the body. A benign tumour can grow but generally will not invade other tissues.

There are 2 major types of uterine cancer:

Adenocarcinoma.This type makes up more than 80% of uterine cancers. It develops from cells in the endometrium.One common endometrial adenocarcinoma is called endometrioid carcinoma, and treatment varies depending on the grade of the tumor, how far it goes into the uterus, and the stage or extent of disease (see Stages and Grades). A less common type is called endometrial serous carcinoma. This form is treated like ovarian cancer.

Sarcoma. This type of uterine cancer develops in the supporting tissues of the uterine glands or in the myometrium, which is the uterine muscle. Sarcoma accounts for about 2% to 4% of uterine cancers. In most situations, sarcomas are treated differently than adenocarcinomas. Types of endometrial sarcoma include leiomyosarcoma and endometrial stromal sarcoma

The most common symptom of endometrial cancer is abnormal vaginal bleeding, ranging from a watery and blood-streaked flow to a flow that contains more blood. Vaginal bleeding, during or after menopause, is often a sign of a problem.

Symptoms for uterine cancer include:

  • Vaginal bleeding or spotting after menopause
  • New onset of heavy menstrual periods or bleeding between periods
  • A watery pink or white discharge from the vagina
  • Two or more weeks of persistent pain in the lower abdomen or pelvic area

These symptoms may be caused by cancer or by other health problems. It is important for a woman to see her doctor if she is having any of these symptoms.


When a woman experiences concerning symptoms, a pelvic exam, including a rectovaginal exam, and a general physical should be performed. If the exam is abnormal, the woman should undergo an endometrial biopsy, ultrasound and/or and a D&C (dilation and curettage) procedure.

  • The stage, grade and specific subtype (histology) of your cancer
  • The size and location of your cancer
  • Your age and general health

Uterine cancer is usually treated with surgery.

Surgery involves removal of uterus tube and ovary along with pelvic lymph nodes.This can be done via open, laparoscopic or robotic approch.

Your specific treatment plan will depend on several factors, including:

  • The stage, grade and specific subtype (histology) of your cancer
  • The size and location of your cancer
  • Your age and general health

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